Detalhe da pesquisa
1.
Na+ controls hypoxic signalling by the mitochondrial respiratory chain.
Nature
; 586(7828): 287-291, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32728214
2.
m-Terphenylamines, Acting as Selective COX-1 Inhibitors, Block Microglia Inflammatory Response and Exert Neuroprotective Activity.
Molecules
; 28(14)2023 Jul 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37513247
3.
Neuroprotective effect of melatonin against ischemia is partially mediated by alpha-7 nicotinic receptor modulation and HO-1 overexpression.
J Pineal Res
; 56(2): 204-12, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24350834
4.
Guanosine controls inflammatory pathways to afford neuroprotection of hippocampal slices under oxygen and glucose deprivation conditions.
J Neurochem
; 126(4): 437-50, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23713463
5.
Melatonin Reduces NLRP3 Inflammasome Activation by Increasing α7 nAChR-Mediated Autophagic Flux.
Antioxidants (Basel)
; 9(12)2020 Dec 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33353046
6.
Early toll-like receptor 4 blockade reduces ROS and inflammation triggered by microglial pro-inflammatory phenotype in rodent and human brain ischaemia models.
Br J Pharmacol
; 176(15): 2764-2779, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31074003
7.
Ischemic brain injury: New insights on the protective role of melatonin.
Free Radic Biol Med
; 104: 32-53, 2017 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28065781
8.
Targeting Nrf2 in Protection Against Renal Disease.
Curr Med Chem
; 24(33): 3583-3605, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28494744
9.
Mitochondrial complex I deactivation is related to superoxide production in acute hypoxia.
Redox Biol
; 12: 1040-1051, 2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28511347
10.
Melatonin protects against oxygen and glucose deprivation by decreasing extracellular glutamate and Nox-derived ROS in rat hippocampal slices.
Neurotoxicology
; 57: 61-68, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27620136
11.
Agmatine, by Improving Neuroplasticity Markers and Inducing Nrf2, Prevents Corticosterone-Induced Depressive-Like Behavior in Mice.
Mol Neurobiol
; 53(5): 3030-3045, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-25966970
12.
Anti-inflammatory role of microglial alpha7 nAChRs and its role in neuroprotection.
Biochem Pharmacol
; 97(4): 463-472, 2015 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26232730
13.
Microglial HO-1 induction by curcumin provides antioxidant, antineuroinflammatory, and glioprotective effects.
Mol Nutr Food Res
; 59(9): 1690-700, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26047311
14.
The melatonin-N,N-dibenzyl(N-methyl)amine hybrid ITH91/IQM157 affords neuroprotection in an in vitro Alzheimer's model via hemo-oxygenase-1 induction.
ACS Chem Neurosci
; 6(2): 288-96, 2015 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-25393881
15.
Melatonin-sulforaphane hybrid ITH12674 induces neuroprotection in oxidative stress conditions by a 'drug-prodrug' mechanism of action.
Br J Pharmacol
; 172(7): 1807-21, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25425158
16.
Alpha7 nicotinic receptor activation protects against oxidative stress via heme-oxygenase I induction.
Biochem Pharmacol
; 97(4): 473-481, 2015 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26212551
17.
Neuroprotective mechanism of the novel melatonin derivative Neu-P11 in brain ischemia related models.
Neuropharmacology
; 99: 187-95, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26188145
18.
New 5-unsubstituted dihydropyridines with improved CaV1.3 selectivity as potential neuroprotective agents against ischemic injury.
J Med Chem
; 57(10): 4313-23, 2014 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-24754640
19.
The microglial α7-acetylcholine nicotinic receptor is a key element in promoting neuroprotection by inducing heme oxygenase-1 via nuclear factor erythroid-2-related factor 2.
Antioxid Redox Signal
; 19(11): 1135-48, 2013 Oct 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-23311871
20.
Nrf2 participates in depressive disorders through an anti-inflammatory mechanism.
Psychoneuroendocrinology
; 38(10): 2010-22, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23623252